Comprehensive pan-cancer analysis indicates key gene of p53-independent apoptosis is a novel biomarker for clinical application and chemotherapy in colorectal cancer
The expression level of SLFN11 has a substantial promise as a valuable biomarker for diagnosis and a predictive indicator for assessing the effectiveness of chemotherapy and immunotherapy in human cancers, which deserves further additional basic experiments and clinical trials to prove.
Authors
- Jianing Yan (ORCID: https://orcid.org/0000-0002-8781-9021)
- Yongfu Shao (ORCID: https://orcid.org/0000-0001-6256-1426)
- Min Miao
- Jingzhi Wang (ORCID: https://orcid.org/0000-0001-6439-9805)
Institutions
- Ningbo University (CN)
- Nantong University (CN)
- Yancheng First People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-03-27
- DOI
- https://doi.org/10.3389/fimmu.2025.1571137
- Primary Topic
- PARP inhibition in cancer therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00