Determination of the genome-scale metabolic network of Bartonella quintana str. Toulouse to optimize growth for its use as chassis for synthetic biology

This study represents a step toward developing <i>B. quintana</i> as a viable chassis for synthetic biology applications. The reconstructed metabolic model provides a comprehensive understanding of <i>B. quintana</i>'s metabolic capabilities, identifying essential pathways and growth limitations. While metabolic predictions align with experimental results in key aspects, further refinements are needed to enhance model accuracy and optimize growth conditions.