Fe‐Catalyzed C‐N/C‐S Bonds Formation via Activation of Csp<sup>3</sup>‐H Bond of Methylarenes: A Straightforward Tandem Oxidative Process to Access Benzazoles
ABSTRACT Fe‐catalyzed tandem cross‐dehydrogenative coupling of the methylarenes with o ‐phenylenediamine/2‐aminothiophenol as coupling partners has been developed for the synthesis of benzimidazoles and benzothiazoles. Various 2‐aryl benzimidazoles/thiazoles were synthesized with high efficiency from cost‐effective raw materials using tert ‐butyl hydroperoxide (TBHP) as an environmentally benign oxidant without any co‐promoter and additional oxidizing reagent.
Authors
- Jasem Aboonajmi (ORCID: https://orcid.org/0000-0003-0022-9908)
- Dariush Khalili (ORCID: https://orcid.org/0000-0003-2266-4492)
- Fatemeh Bigdelizadeh
Institutions
- Shiraz University (IR)
Publication Details
- Journal
- Applied Organometallic Chemistry
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1002/aoc.70130
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shiraz University