High vs. low vancomycin therapeutic concentrations in periprosthetic joint infection: A retrospective cohort analysis
Maintaining vancomycin concentrations of 15-20 μg/mL is associated with better infection control for PJI patients who present with higher synovial WBC account, without compromising patient safety, joint function, or long-term quality of life.
Authors
- Wang De-hua
- Jingdong Cheng (ORCID: https://orcid.org/0000-0003-4442-377X)
- Qianyi Ou
- Xinyu Li (ORCID: https://orcid.org/0000-0003-3433-3009)
- Yanqing Chen (ORCID: https://orcid.org/0000-0003-3092-1823)
- Liangming Zhang (ORCID: https://orcid.org/0009-0002-5163-4954)
- Qingqing Zhao
Institutions
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Panzhihua Central Hospital (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-03-27
- DOI
- https://doi.org/10.3389/fphar.2025.1555276
- Citations
- 1
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.01