Exploring the repurposed role of solithromycin as an antivirulence agent against Staphylococcus aureus and its resistant variants

This study highlights the potential of SOL as an antivirulence agent, emphasizing the importance of targeting regulators, such as <i>ΔagrA</i>, in managing <i>S. aureus</i> infections.

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Publication Details

Journal
Frontiers in Microbiology
Published
2025-03-27
DOI
https://doi.org/10.3389/fmicb.2025.1540997
Primary Topic
Antimicrobial Resistance in Staphylococcus
Type
article
Field-Weighted Citation Impact
0.00
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article

Exploring the repurposed role of solithromycin as an antivirulence agent against Staphylococcus aureus and its resistant variants

Rihaf Alfaraj, Fai A. Alkathiri, Sarah H. Alanazi, Lama A. Alamri et al.
Frontiers in Microbiology
Antimicrobial Resistance in Staphylococcus
article

Exploring the repurposed role of solithromycin as an antivirulence agent against Staphylococcus aureus and its resistant variants

Rihaf Alfaraj, Fai A. Alkathiri, Sarah H. Alanazi, Lama A. Alamri, Najd B. Alnassar, Razan A. Algarni, Norah S. Alhabdan, Reema A. Abuthnain
article en

Abstract

This study highlights the potential of SOL as an antivirulence agent, emphasizing the importance of targeting regulators, such as <i>ΔagrA</i>, in managing <i>S. aureus</i> infections.

Frontiers in MicrobiologyVol. 16
King Saud University (SA)
Openalex Percentile: Top 92%
Antimicrobial Resistance in Staphylococcus
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