Canadian Survey on the Diagnosis and Clinical Management of Preterm Premature Rupture of Membranes in Tertiary Centres
This study examines diagnostic and management practices for preterm premature rupture of membranes before 34 weeks in Canada. Between August and November 2023, obstetricians from the Canadian Preterm Birth Network (28 sites) completed an online survey. The response rate was 79% (n = 22). Preferred diagnostic tests include the fern test (91%) and nitrazine paper test (77%). Home management is offered in 64% of sites. The most used antibiotherapy (55%) combines macrolide and ampicillin followed by amoxicillin. Group B Streptococcus status rarely influences delivery timing (86%). Four sites have no management protocol. Preterm premature rupture of membranes management varies across Canada, highlighting the need for standardization.
Authors
- Stefania Ronzoni (ORCID: https://orcid.org/0000-0001-6290-5524)
- Isabelle Boucoiran (ORCID: https://orcid.org/0000-0001-9545-6024)
- Rohan D’Souza (ORCID: https://orcid.org/0000-0002-4049-2017)
- Joseph Ting (ORCID: https://orcid.org/0000-0002-5246-8823)
- Sarah D. McDonald (ORCID: https://orcid.org/0000-0002-4461-2178)
- Romy Barbera
- Marc Beltempo
Institutions
- Mount Sinai Hospital (CA)
- Sunnybrook Health Science Centre (CA)
- University of British Columbia (CA)
- University of Toronto (CA)
- Montreal Children's Hospital (CA)
- Centre Hospitalier Universitaire Sainte-Justine (CA)
- Health Sciences Centre (CA)
- McGill University (CA)
- Université de Montréal (CA)
- McMaster University (CA)
Publication Details
- Journal
- Journal of Obstetrics and Gynaecology Canada
- Published
- 2025-03-27
- DOI
- https://doi.org/10.1016/j.jogc.2025.102822
- Primary Topic
- Preterm Birth and Chorioamnionitis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Foundation for the National Institutes of Health
- Canadian Institutes of Health Research