Long-term remission in a patient with NK/T cell intravascular lymphoma with autologous hematopoietic cell transplantation

Intravascular lymphoma (IVL) is a rare subtype of lymphoma, mostly of B-cell origin. A few cases of IVL have been reported as having NK/T cell origins (IVNKTL). These cases are known to be fatal, especially when systemic symptoms are present. We report the case of a patient of IVNKTL who was refractory to initial treatment and received autologous hematopoietic stem cell transplantation (auto-HSCT). She has maintained complete remission (CR) for over eight years. Our case might support the evidence of auto-HSCT for the treatment of IVNKTL with chemosensitivity.

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Publication Details

Journal
Journal of Clinical and Experimental Hematopathology
Published
2025-03-27
DOI
https://doi.org/10.3960/jslrt.24068
Primary Topic
CNS Lymphoma Diagnosis and Treatment
Type
article
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article

Long-term remission in a patient with NK/T cell intravascular lymphoma with autologous hematopoietic cell transplantation

Atsushi Hamamura, Shigeo Toyota, Hiroki Tsutsumi, Keisuke Tanaka et al.
Journal of Clinical and Experimental Hematopathology
CNS Lymphoma Diagnosis and Treatment
article

Long-term remission in a patient with NK/T cell intravascular lymphoma with autologous hematopoietic cell transplantation

Atsushi Hamamura, Shigeo Toyota, Hiroki Tsutsumi, Keisuke Tanaka, Norihiko Nakamura
article en

Abstract

Intravascular lymphoma (IVL) is a rare subtype of lymphoma, mostly of B-cell origin. A few cases of IVL have been reported as having NK/T cell origins (IVNKTL). These cases are known to be fatal, especially when systemic symptoms are present. We report the case of a patient of IVNKTL who was refractory to initial treatment and received autologous hematopoietic stem cell transplantation (auto-HSCT). She has maintained complete remission (CR) for over eight years. Our case might support the evidence of auto-HSCT for the treatment of IVNKTL with chemosensitivity.

Journal of Clinical and Experimental HematopathologyVol. 65(1)
Tokyo Medical and Dental University (JP), Tokyo Metropolitan Komagome Hospital (JP), Saitama Cancer Center (JP), Yokosuka Kyosai Hospital (JP)
Good health and well-being
Openalex Percentile: Top 90%
CNS Lymphoma Diagnosis and Treatment
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