Ultrasound irradiation activates purine metabolism and mitochondrial respiration via the MAPK signaling pathway in myotubes
This study investigated the impact of US irradiation on myotubes using genomic analysis, metabolomic analysis, and mitochondrial function. US irradiation activated the MAPK signaling pathway, which in turn enhanced purine metabolism and improved mitochondrial respiration.
Authors
- Jihao Xing
- Yamin Fu (ORCID: https://orcid.org/0009-0001-4993-9903)
- Hidemi Fujino (ORCID: https://orcid.org/0000-0002-6304-0654)
- Noriaki Maeshige (ORCID: https://orcid.org/0000-0002-3573-347X)
- Qingcheng Guo (ORCID: https://orcid.org/0000-0002-7240-0076)
- Atomu Yamaguchi (ORCID: https://orcid.org/0009-0009-4046-5156)
- Xiaoqi Ma (ORCID: https://orcid.org/0000-0003-0074-4192)
- Fuwen Lu
- Lin Hao (ORCID: https://orcid.org/0000-0002-0828-3581)
- Hiroyo Kondo
Institutions
- Shubun University (JP)
- Shanghai Sunshine Rehabilitation Center (CN)
- Kobe University (JP)
Publication Details
- Journal
- Biochemistry and Biophysics Reports
- Published
- 2025-03-27
- DOI
- https://doi.org/10.1016/j.bbrep.2025.101984
- Primary Topic
- Ultrasound and Hyperthermia Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Society for the Promotion of Science
- Japan Science and Technology Agency