<b>Coinfections among patients with COVID-19: A retrospective analysis</b>

Background: From 2019 to 2021, the world was caught in the grappling clutches of the novel coronavirus, claiming almost 6.9 million lives, thus adding to the burden on the healthcare system. Aim: We aim to determine the rate of co-infections in COVID-19-affected individuals, describe their characteristics, and compare their mortality rates. Methods: Patients admitted with COVID-19 pneumonia between June 2020 and March 2021 who tested positive were identified from the hospital RT-PCR records, and their data was collected using the hospital information system. The primary outcome of this study was the all-cause in-hospital mortality. Proportions were compared using the Fisher exact test, and continuous variables were compared using the student t-test. Results: Data suggests that the most common co-infection was bacterial pneumonia (36.7%). Even though mortality was observed, it was not statistically significant. The mean length of stay in co-infected patients (11 days) was longer than in patients without co-infections. On univariate analysis, there was a significantly higher value of CRP in patients with co-infection than in patients without co-infection. Conclusion: This study sheds light on the complex interplay between co-infections and their outcomes, adding to the research needed to optimise patient care in a similar future pandemic.

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Publication Details

Journal
International Journal of Medical Science and Public Health
Published
2025-01-01
DOI
https://doi.org/10.5455/ijmsph.2025.v11.i1.2
Primary Topic
Antibiotic Use and Resistance
Type
article
Field-Weighted Citation Impact
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article

Coinfections among patients with COVID-19: A retrospective analysis

Neetha S. Murthy, R Deepashree, Sowmya Gopalan, Ranjitha Shankaregowda et al.
International Journal of Medical Science and Public Health
Antibiotic Use and Resistance
article

Coinfections among patients with COVID-19: A retrospective analysis

Neetha S. Murthy, R Deepashree, Sowmya Gopalan, Ranjitha Shankaregowda, Vidyavathi B. Chitharagi, Subramaniam Sujatha, Rashmi P. Mahale, Amod K. Agrawal, A Tejashree, Madhumathi Rao, Mahadevaiah Neelambike Sumana, Hema S Pinnam, Isha A Kumthekar
article en

Abstract

Background: From 2019 to 2021, the world was caught in the grappling clutches of the novel coronavirus, claiming almost 6.9 million lives, thus adding to the burden on the healthcare system. Aim: We aim to determine the rate of co-infections in COVID-19-affected individuals, describe their characteristics, and compare their mortality rates. Methods: Patients admitted with COVID-19 pneumonia between June 2020 and March 2021 who tested positive were identified from the hospital RT-PCR records, and their data was collected using the hospital information system. The primary outcome of this study was the all-cause in-hospital mortality. Proportions were compared using the Fisher exact test, and continuous variables were compared using the student t-test. Results: Data suggests that the most common co-infection was bacterial pneumonia (36.7%). Even though mortality was observed, it was not statistically significant. The mean length of stay in co-infected patients (11 days) was longer than in patients without co-infections. On univariate analysis, there was a significantly higher value of CRP in patients with co-infection than in patients without co-infection. Conclusion: This study sheds light on the complex interplay between co-infections and their outcomes, adding to the research needed to optimise patient care in a similar future pandemic.

International Journal of Medical Science and Public HealthVol. 11(1)
Openalex Percentile: Top 90%
Antibiotic Use and Resistance
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