Bridging the gap: overcoming barriers to implementing gene expression profiling in clinical practice

Precision oncology aims to transform cancer treatment by enabling more tailored therapeutic strategies based on the molecular characteristics of each patient’s tumor. Gene expression profiling (GEP) assays play a critical role in this paradigm shift, providing insights into tumor biology, prognosis, and potential treatment responses.1 In breast cancer, GEP assays have demonstrated significant value in guiding clinical decisions, particularly in tailoring adjuvant chemotherapy for patients with luminal-like breast cancer.

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Journal
ESMO Real World Data and Digital Oncology
Published
2025-03-27
DOI
https://doi.org/10.1016/j.esmorw.2025.100128
Primary Topic
Molecular Biology Techniques and Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

Bridging the gap: overcoming barriers to implementing gene expression profiling in clinical practice

Alexios Matikas, Antonios Valachis
ESMO Real World Data and Digital Oncology
Molecular Biology Techniques and Applications
article

Bridging the gap: overcoming barriers to implementing gene expression profiling in clinical practice

Alexios Matikas, Antonios Valachis
article en

Abstract

Precision oncology aims to transform cancer treatment by enabling more tailored therapeutic strategies based on the molecular characteristics of each patient’s tumor. Gene expression profiling (GEP) assays play a critical role in this paradigm shift, providing insights into tumor biology, prognosis, and potential treatment responses.1 In breast cancer, GEP assays have demonstrated significant value in guiding clinical decisions, particularly in tailoring adjuvant chemotherapy for patients with luminal-like breast cancer.

ESMO Real World Data and Digital OncologyVol. 8
Örebro University (SE), Karolinska Institutet (SE)
Openalex Percentile: Top 95%
Molecular Biology Techniques and Applications
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