m5C methylation of mitochondrial RNA and non-coding RNA by NSUN3 is associated with variant gene expression and asexual blood-stage development in Plasmodium falciparum
Our findings demonstrate a vital role of PfNSUN3 in the process of the mutually exclusive expression of variant genes, and contribute to a better understanding of the complex mechanism of epigenetic regulation of gene expression in P. falciparum.
Authors
- Qingfeng Zhang (ORCID: https://orcid.org/0000-0002-8759-9102)
- Fengshuo Zhang (ORCID: https://orcid.org/0009-0006-4281-9147)
- Ye Hu (ORCID: https://orcid.org/0000-0001-9664-9426)
- Yanting Fan (ORCID: https://orcid.org/0000-0002-0526-1192)
- Ruoyu Tang (ORCID: https://orcid.org/0000-0001-9979-061X)
- Xuan Chen (ORCID: https://orcid.org/0000-0001-5553-3638)
- Fei Wang (ORCID: https://orcid.org/0000-0001-9539-8397)
- Junlong Yang
- Zuping Zhang (ORCID: https://orcid.org/0000-0002-3295-2861)
- Yanli Bai (ORCID: https://orcid.org/0000-0002-2997-4795)
- Binbin Lu (ORCID: https://orcid.org/0000-0001-9832-9995)
- Xuanjin Du
- Xiaomin Shang
Institutions
- Jiangxi University of Traditional Chinese Medicine (CN)
- Tongji University (CN)
- Central South University (CN)
- Northwest University (CN)
- Shanghai East Hospital (CN)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2025-03-27
- DOI
- https://doi.org/10.1186/s13071-025-06746-7
- Citations
- 1
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hainan Province