Efficacy, safety, and bleeding risk factor analysis of oral anticoagulants in AF patients ≥ 65 years of age: a multicenter retrospective cohort study
Compared with warfarin, NOACs significantly reduced the risk of minor bleeding, all-cause mortality, and there were no statistically significant differences in major bleeding or thrombotic events. NOACs were not more effective than warfarin in thrombotic and bleeding events, regardless of the subgroup analyses on age, male, BMI and comorbid hypertension and diabetes.
Authors
- Peiguang Niu (ORCID: https://orcid.org/0000-0002-9262-9716)
- Xinhai Huang (ORCID: https://orcid.org/0000-0003-4960-9792)
- Jiana Chen (ORCID: https://orcid.org/0000-0001-5779-1972)
- Jinhua Zhang (ORCID: https://orcid.org/0000-0002-5629-0348)
- Xiaomin Dong
- Cuifang You
- Yanxian Lan
- Shuzheng Jiang
Institutions
- Fujian Medical University (CN)
- Guilin Medical University (CN)
- Ningde Normal University (CN)
- Fuzhou Maternity and Child Health Care Hospital (CN)
- Riverside Hospital of Guangxi Zhuang Autonomous Region (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- BMC Geriatrics
- Published
- 2025-03-27
- DOI
- https://doi.org/10.1186/s12877-025-05838-4
- Citations
- 3
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 4.16