Prevalence of CMV glycoprotein B genotypes in newborns with congenital CMV infection in Southern Bahia, Brazil
Cytomegalovirus (CMV) is a common herpesvirus that causes congenital infections with significant neonatal health risks. This study characterized CMV glycoprotein B (gB) genotypes among 2,595 newborns in Southern Bahia, Brazil. CMV DNA was detected in 1.19% of cases, with gB1, gB2, and gB3 identified among the infected infants (gB2 and gB1 being the most prevalent). Although follow-up evaluations showed no statistically significant correlation between genotypes and late sequelae, three infants exhibited hearing loss. These findings highlight the predominance of gB1 and gB2 in the studied region, emphasizing the need for targeted prevention and management strategies.
Authors
- Lauro Juliano Marin (ORCID: https://orcid.org/0000-0002-1292-9330)
- Uener Ribeiro dos Santos (ORCID: https://orcid.org/0000-0003-1193-5453)
- Luciana Debortoli de Carvalho (ORCID: https://orcid.org/0000-0002-4213-1370)
- Pérola Rodrigues dos Santos (ORCID: https://orcid.org/0000-0003-1042-4563)
- Víctor Hugo Aquino (ORCID: https://orcid.org/0000-0003-1910-0776)
- Sandra Rocha Gadelha (ORCID: https://orcid.org/0000-0002-3079-488X)
- Marcelo Bezerra de Menezes (ORCID: https://orcid.org/0000-0001-9328-0125)
- Felipe Charu Ramos
Publication Details
- Journal
- Brazilian Journal of Development
- Published
- 2025-03-27
- DOI
- https://doi.org/10.34117/bjdv11n3-050
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00