Acupuncture for Essential Hypertension and Endothelial Dysfunction: A Randomized Clinical Trial
Introduction Arterial hypertension (AH) is one of the main modifiable risk factors for cardiovascular diseases, as it causes increased arterial stiffness and endothelial dysfunction since early stages. Sympathetic hyperactivity and activation of the renin-angiotensin-aldosterone system (RAAS) are among the major pathophysiological mechanisms of AH, in addition to an overproduction of reactive oxygen species (ROS) and imbalances in the nitric oxide (NO) availability. The increase in endothelial permeability in response to low NO synthesis explains the correlation of AH with atherosclerosis [...]
Authors
- Priscila Valverde de Oliveira Vitorino (ORCID: https://orcid.org/0000-0002-5487-4649)
- Mikaelle Costa Correia (ORCID: https://orcid.org/0000-0002-0954-4261)
- Alexandre Massao Yoshizumi
- Ana Luíza Lima Sousa (ORCID: https://orcid.org/0000-0002-7566-3541)
- Weimar Kunz Sebba Barroso (ORCID: https://orcid.org/0000-0002-1265-1930)
- Amanda Rodrigues Bitencourt (ORCID: https://orcid.org/0009-0007-9132-2310)
Institutions
- Hospital Israelita Albert Einstein (BR)
- Pontifícia Universidade Católica de Goiás (BR)
- Universidade Federal de Goiás (BR)
Publication Details
- Journal
- Arquivos Brasileiros de Cardiologia
- Published
- 2025-01-01
- DOI
- https://doi.org/10.36660/abc.20240596i
- Primary Topic
- Cardiovascular Health and Disease Prevention
- Type
- article
- Field-Weighted Citation Impact
- 0.00