Unleashing the Potential of Givinostat: A Novel Therapy for Duchenne Muscular Dystrophy

Givinostat represents a paradigm shift in DMD management, offering benefits beyond corticosteroids by reducing fibrosis and promoting muscle regeneration. While its long-term safety and cost-effectiveness require further evaluation, its combination potential with gene therapies highlights its importance in future DMD treatment strategies. Ongoing studies aim to refine its role in broader neuromuscular disorders.

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Publication Details

Journal
Current Therapeutic Research
Published
2025-01-01
DOI
https://doi.org/10.1016/j.curtheres.2025.100787
Citations
4
Primary Topic
Muscle Physiology and Disorders
Type
article
Field-Weighted Citation Impact
3.22
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article

Unleashing the Potential of Givinostat: A Novel Therapy for Duchenne Muscular Dystrophy

Ahmad Furqan Anjum, Muhammad Burhan Anjum, Raza Ur Rehman
4 citations
Current Therapeutic Research
Muscle Physiology and Disorders
3.22
article

Unleashing the Potential of Givinostat: A Novel Therapy for Duchenne Muscular Dystrophy

Ahmad Furqan Anjum, Muhammad Burhan Anjum, Raza Ur Rehman
article en
4 citations

Abstract

Givinostat represents a paradigm shift in DMD management, offering benefits beyond corticosteroids by reducing fibrosis and promoting muscle regeneration. While its long-term safety and cost-effectiveness require further evaluation, its combination potential with gene therapies highlights its importance in future DMD treatment strategies. Ongoing studies aim to refine its role in broader neuromuscular disorders.

Current Therapeutic ResearchVol. 102
Farooq Hospital (PK), Shaikh Zayed Postgraduate Medical Institute (PK)
Openalex Percentile: Top 9%
Muscle Physiology and Disorders
3.22
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