In vitro isolation of contemporary Treponema pallidum strains directly from clinical samples of syphilis patients
The introduced in vitro protocol enables isolation of T. pallidum from clinical material, including frozen samples, without the need for experimental rabbits. This method facilitates the isolation of contemporary, clinically relevant treponemal strains.
Authors
- David Šmajs (ORCID: https://orcid.org/0000-0002-4176-3464)
- Matěj Hrala
- Petra Pospíšilová (ORCID: https://orcid.org/0000-0002-4732-5051)
- Juraj Bosák (ORCID: https://orcid.org/0000-0001-7136-8396)
- Eliška Vrbová
- Miroslav Nečas
- Hana Jedličková
- Radim Strnadel
- Filip Skokan
Institutions
- Masaryk University (CZ)
- University Hospital Brno (CZ)
Publication Details
- Journal
- Clinical Microbiology and Infection
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1016/j.cmi.2025.03.017
- Citations
- 3
- Primary Topic
- Syphilis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.49