Editorial for JUO 2025 Vol. 23 No. 1 - Highlights of This Issue’s Papers and the JUO Editors’ Pick

In 2025, Journal of Urologic Oncology (JUO) will strive to clarify new findings reported in the urological oncology community and communicate them to readers using a rational description method and clear format through leading compliance with reporting guidelines while meeting international standards.In the fields of prostate cancer, kidney cancer, and bladder cancer, which are developing day by day, we aim to comprehensively convey the latest knowledge through a review article on a timely topic in each volume and to deliver an original article with a clinically important issue or a fresh perspective that has not been seen in other journals. Prostate CancerThis month's prostate cancer review is a comprehensive look at precision medicine for prostate cancer by Professors Gabriela M. Diaz and Michael S. Leapman [1] of Yale University in the United States.It provides a compelling forecast that artificial intelligence technology, biomarkers, and new imaging diagnostic technologies will enable more precise predictions and treatment choices in the complex field of prostate cancer with heterogeneity.It is common in clinical practice that many patients dia gnosed with prostate cancer develop anxiety and depression, but the extent to which this affects the prognosis of treatment has not been well understood.Professors Elliott J. Druten and Jonathan Heinlen [2] of the University of Oklahoma in the United States conducted a survey of 489 patients at a single institution, Of these, 92% reported minimal or mild depression, and 8% of patients reported moderate to severe depression.The degree of postalcohol complications, espe cially incontinence, had a statistical association with the degree of depression in all periods of this study, which was observed up to 12 months after alcohol consumption, sug gesting that consideration of psychological status should be provided in the management of patients after surgery.As radiation therapy tends to deliver higherenergy radia tion over a shorter treatment period, installing a barrier that can provide effective protection for adjacent organs, espec ially the rectum, can be an important means of increasing the efficiency of treatment and reducing complications.