Cytokine pattern during asymptomatic Anaplasma spp. infections and effect of co-infections by malaria and helminths in schoolchildren of Franceville, southeastern Gabon

These results suggest that infection with Anaplasma spp. downregulates cytokines including IL-6, IL-22 and TGF-β and that co-infection with Plasmodium spp. might have a protective effect on the host, while co-infection with helminths might have a negative effect.

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Publication Details

Journal
Parasites & Vectors
Published
2025-03-27
DOI
https://doi.org/10.1186/s13071-025-06714-1
Primary Topic
Vector-borne infectious diseases
Type
article
Field-Weighted Citation Impact
0.00

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article

Cytokine pattern during asymptomatic Anaplasma spp. infections and effect of co-infections by malaria and helminths in schoolchildren of Franceville, southeastern Gabon

Jean Claude Biteghe-Bi-Essone, Nal Kennedy Ndjangangoye, Nancy Diamella Moukodoum, Chérone Nancy Mbani Mpega Ntigui et al.
Parasites & Vectors
Vector-borne infectious diseases
article

Cytokine pattern during asymptomatic Anaplasma spp. infections and effect of co-infections by malaria and helminths in schoolchildren of Franceville, southeastern Gabon

Jean Claude Biteghe-Bi-Essone, Nal Kennedy Ndjangangoye, Nancy Diamella Moukodoum, Chérone Nancy Mbani Mpega Ntigui, Roméo Karl Imboumy Limoukou, Sandrine Lydie Oyegue-Liabagui, Jean-Bernard Lékana-Douki, Alain Prince Okouga, Lady Charlène Kouna, Steede Seinnat Ontoua, Roland Fabrice Kassa Kassa, Félicien Bagueboussa, Jenny Mouloungui-Mavoungou, Desly Luide Madoungou Idoumi
article en

Abstract

These results suggest that infection with Anaplasma spp. downregulates cytokines including IL-6, IL-22 and TGF-β and that co-infection with Plasmodium spp. might have a protective effect on the host, while co-infection with helminths might have a negative effect.

Parasites & VectorsVol. 18(1)
Université des Sciences de la Santé (GA), Centre International de Recherches Médicales de Franceville (GA), Université des Sciences et Techniques de Masuku (GA)
European and Developing Countries Clinical Trials Partnership
Good health and well-being
Openalex Percentile: Top 94%
Vector-borne infectious diseases
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Cytokine pattern during asymptomatic Anaplasma spp. infections and effect of co-infections by malaria and helminths in schoolchildren of Franceville, southeastern Gabon — Jean Claude Biteghe-Bi-Essone, Nal Kennedy Ndjangangoye, et al. · Parasites & Vectors (2025) | TGRS Research Map | TGRS