Bridging the Gap: A Mixed-Methods Study on Factors Influencing Breast Cancer Clinicians’ Decisions to Use Clinical Prediction Models

Accessibility, cost, and practical considerations, such as ease of use and clinical utility, were prioritized slightly more than technical validation metrics, such as discrimination and calibration, when deciding to start using a clinical prediction model.Most breast cancer clinicians valued models with clear inputs (e.g., variable definitions, cutoffs) and outputs; few were interested in the exact model specifications.Perceptual or subjective factors, including perceived accuracy and peer acceptability, also influenced model adoption but were secondary to practical considerations.Sociodemographic variables, such as clinical specialization and hospital setting, influenced the importance of factors for model use.