The GCN4-Swi6B module mediates low nitrogen-induced cell wall remodeling in <i>Ganoderma lucidum</i>
To survive in stressful environments, fungi initiate cell wall remodeling pathways to adaptively modify the cell wall composition and structure. Here, we found that nitrogen deficiency upregulated the cell wall polysaccharide content and cell wall thickness through the GCN4-SWI6B signaling pathway. Our findings provide valuable insights into the environmental adaptation of fungal cell walls, contributing to a deeper understanding of fungal responses to environmental stress.
Authors
- Huhui Chen (ORCID: https://orcid.org/0000-0002-9469-8424)
- Jing Zhu (ORCID: https://orcid.org/0000-0003-0694-7812)
- Mingwen Zhao (ORCID: https://orcid.org/0000-0002-9413-1743)
- Liang Shi (ORCID: https://orcid.org/0009-0002-8205-7037)
- Lingshuai Wang
- Lingyan Shi
- Ang Ren (ORCID: https://orcid.org/0000-0002-8597-7755)
- Rui Liu (ORCID: https://orcid.org/0000-0002-8534-2071)
Institutions
- Nanjing Agricultural University (CN)
- Ministry of Agriculture and Rural Affairs (CN)
Publication Details
- Journal
- Applied and Environmental Microbiology
- Published
- 2025-03-27
- DOI
- https://doi.org/10.1128/aem.00164-25
- Citations
- 3
- Primary Topic
- Fungal Biology and Applications
- Type
- article
- Field-Weighted Citation Impact
- 4.18
Funders
- National Natural Science Foundation of China
- Earmarked Fund for China Agriculture Research System