Rapid Determination of Isotopic Purity of Stable Isotope (D, <sup>15</sup> N, or <sup>13</sup> C)‐Labeled Organic Compounds by Electrospray Ionization‐High‐Resolution Mass Spectrometry
Finally, a workflow with a Python calculation program was summarized for determinations of the isotopic purity for mono isotope-labeled or mixed isotopes-labeled organic compounds, involving D, <sup>15</sup>N, or <sup>13</sup>C, by using ESI-HRMS to assign the representative isotopolog ions with accurate mass and excluding the isobar interference.
Authors
- Chenlong Liang (ORCID: https://orcid.org/0009-0006-5206-3048)
- Lin Ling (ORCID: https://orcid.org/0000-0001-8182-1481)
- Haoyang Wang (ORCID: https://orcid.org/0000-0002-4058-240X)
Institutions
- University of Shanghai for Science and Technology (CN)
- Chinese Academy of Sciences (CN)
- Shanghai Institute of Organic Chemistry (CN)
Publication Details
- Journal
- Rapid Communications in Mass Spectrometry
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1002/rcm.10031
- Primary Topic
- Isotope Analysis in Ecology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences