Cardiovascular rate pressure product is associated with NfL in older adults at risk for AD
We explored the relationship between RPP and CSF analytes.Higher RPP was associated with higher NfL but not other measured CSF biomarkers.HR was positively associated with NfL, whereas SBP was not.
Authors
- Yue Ma (ORCID: https://orcid.org/0000-0003-1362-3752)
- Barbara B. Bendlin (ORCID: https://orcid.org/0000-0002-0580-9875)
- Catherine L. Gallagher (ORCID: https://orcid.org/0000-0002-1701-6362)
- Joe Strong
- Nathaniel A. Chin (ORCID: https://orcid.org/0000-0001-8008-9356)
- Gwendlyn Kollmorgen
- Kaj Blennow
- Sarah Lose
- Jacqueline Pontes Monteiro (ORCID: https://orcid.org/0000-0001-7141-7776)
- Clara Quijano‐Rubio (ORCID: https://orcid.org/0000-0001-9050-3282)
- Chinenye Cynthia Odo (ORCID: https://orcid.org/0009-0005-4580-5800)
- Ozioma C. Okonkwo (ORCID: https://orcid.org/0009-0009-8764-811X)
- Sterling C. Johnson
- Sanjay Asthana (ORCID: https://orcid.org/0000-0002-3298-6324)
- Cynthia M. Carlsson
- Henrik Zetterberg (ORCID: https://orcid.org/0000-0002-4671-6763)
Institutions
- Roche (Switzerland) (CH)
- University of Science and Technology of China (CN)
- University of Wisconsin–Madison (US)
- Sahlgrenska University Hospital (SE)
- Sorbonne Université (FR)
- Roche Pharma AG (Germany) (DE)
- Geriatric Research Education and Clinical Center (US)
- Institut de Myologie (FR)
- Pitié-Salpêtrière Hospital (FR)
- UK Dementia Research Institute (GB)
- William S. Middleton Memorial Veterans Hospital (US)
- Institut du Cerveau (FR)
- University College London (GB)
- University of Gothenburg (SE)
Publication Details
- Journal
- Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1002/dad2.70086
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Wisconsin Alumni Research Foundation
- Hjärnfonden
- Knut och Alice Wallenbergs Stiftelse
- European Research Council
- National Institute on Aging