Cardiovascular rate pressure product is associated with NfL in older adults at risk for AD

We explored the relationship between RPP and CSF analytes.Higher RPP was associated with higher NfL but not other measured CSF biomarkers.HR was positively associated with NfL, whereas SBP was not.

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Publication Details

Journal
Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring
Published
2025-01-01
DOI
https://doi.org/10.1002/dad2.70086
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Cardiovascular rate pressure product is associated with NfL in older adults at risk for AD

Yue Ma, Barbara B. Bendlin, Catherine L. Gallagher, Joe Strong et al.
Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring
Dementia and Cognitive Impairment Research
article

Cardiovascular rate pressure product is associated with NfL in older adults at risk for AD

Yue Ma, Barbara B. Bendlin, Catherine L. Gallagher, Joe Strong, Nathaniel A. Chin, Gwendlyn Kollmorgen, Kaj Blennow, Sarah Lose, Jacqueline Pontes Monteiro, Clara Quijano‐Rubio, Chinenye Cynthia Odo, Ozioma C. Okonkwo, Sterling C. Johnson, Sanjay Asthana, Cynthia M. Carlsson, Henrik Zetterberg
article en

Abstract

We explored the relationship between RPP and CSF analytes.Higher RPP was associated with higher NfL but not other measured CSF biomarkers.HR was positively associated with NfL, whereas SBP was not.

Alzheimer s & Dementia Diagnosis Assessment & Disease MonitoringVol. 17(1)
Roche (Switzerland) (CH), University of Science and Technology of China (CN), University of Wisconsin–Madison (US), Sahlgrenska University Hospital (SE), Sorbonne Université (FR), Roche Pharma AG (Germany) (DE), Geriatric Research Education and Clinical Center (US), Institut de Myologie (FR), Pitié-Salpêtrière Hospital (FR), UK Dementia Research Institute (GB), William S. Middleton Memorial Veterans Hospital (US), Institut du Cerveau (FR), University College London (GB), University of Gothenburg (SE)
Wisconsin Alumni Research Foundation, Hjärnfonden, Knut och Alice Wallenbergs Stiftelse, European Research Council, National Institute on Aging
Good health and well-being
Openalex Percentile: Top 93%
Dementia and Cognitive Impairment Research
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