Characterization and <i>ex vivo</i> modelling of endodontic infections from the Arabian Gulf region
There was high bacterial diversity in root canal samples from necrotic pulp. Samples were shown to contain antibiotic resistance and virulence genes, with no differences evident between symptomatic and asymptomatic infections. A high number of isolated bacteria were resistant to clinically used antibiotics. Ex vivo biofilm models from clinical samples were successfully developed and reproducibly reflected a polymicrobial composition.
Authors
- Abiola Catherine Senok (ORCID: https://orcid.org/0000-0001-6382-198X)
- David W. Williams (ORCID: https://orcid.org/0000-0002-7351-5131)
- Mohannad Nassar (ORCID: https://orcid.org/0000-0002-0848-0737)
- Rania Nassar (ORCID: https://orcid.org/0000-0001-5543-0137)
- Lobna Mohamed (ORCID: https://orcid.org/0000-0002-7485-5867)
Institutions
- University of Sharjah (AE)
- Mohammed Bin Rashid University of Medicine and Health Sciences (AE)
- Cardiff University (GB)
Publication Details
- Journal
- International Endodontic Journal
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1111/iej.14227
- Primary Topic
- Endodontics and Root Canal Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Sharjah
- Mohammed Bin Rashid University of Medicine and Health Sciences