Evaluating the prognostic significance of the pre-treatment neutrophil-to-lymphocyte and monocyte-to-lymphocyte ratios in 177Lu-DOTATATE PRRT treated patients with advanced metastatic neuroendocrine tumors
Pre-treatment NLR and MLR had an independent prognostic impact on disease progression and OS in PRRT-treated NET patients. This routine, inexpensive CBC-based test in the standard pre-PRRT workup demonstrates the prognostic value and may aid clinicians in the risk stratification of NET patients.
Authors
- Mahesh Kumar Padwal (ORCID: https://orcid.org/0000-0003-4715-1108)
- Rahul V. Parghane
- Bhakti Basu (ORCID: https://orcid.org/0000-0002-7381-6671)
- Sandip Kanti Basu (ORCID: https://orcid.org/0000-0001-6607-2558)
- Amir K Nazar
Institutions
- Bhabha Atomic Research Centre (IN)
- Homi Bhabha National Institute (IN)
- Tata Memorial Hospital (IN)
Publication Details
- Journal
- Endocrine
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1007/s12020-025-04212-z
- Citations
- 1
- Primary Topic
- Neuroendocrine Tumor Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Department of Atomic Energy, Government of India
- Bhabha Atomic Research Centre