Comparative real-world effectiveness of ustekinumab versus anti-TNF in Crohn’s disease: 12-month maintenance phase results from the prospective, observational RUN-CD study using propensity score adjustment

In this 12-month RWE comparison, overall CR rates were similar between UST and anti-TNF. However, among week-16 responders, CR rates were significantly higher with UST. Additionally, UST was associated with a significantly greater improvement in QoL compared with anti-TNF.

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Publication Details

Journal
Journal of Crohn s and Colitis
Published
2025-03-25
DOI
https://doi.org/10.1093/ecco-jcc/jjaf051
Citations
2
Primary Topic
Inflammatory Bowel Disease
Type
article
Field-Weighted Citation Impact
3.63
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article

Comparative real-world effectiveness of ustekinumab versus anti-TNF in Crohn’s disease: 12-month maintenance phase results from the prospective, observational RUN-CD study using propensity score adjustment

Martin Hoffstadt, Wolfgang Mohl, Annika Gauss, Sandra Plachta‐Danielzik et al.
2 citations
Journal of Crohn s and Colitis
Inflammatory Bowel Disease
3.63
article

Comparative real-world effectiveness of ustekinumab versus anti-TNF in Crohn’s disease: 12-month maintenance phase results from the prospective, observational RUN-CD study using propensity score adjustment

Martin Hoffstadt, Wolfgang Mohl, Annika Gauss, Sandra Plachta‐Danielzik, Romina di Giuseppe, Raja Atreya, Bernd Bokemeyer, Stefan Schreiber, Niels Teich, Petra Hartmann, Herbert Deppe, Manfred von der Ohe, Thomas Krause, Axel Schweitzer, Elena Gilman, Irina Blumenstein
article en
2 citations

Abstract

In this 12-month RWE comparison, overall CR rates were similar between UST and anti-TNF. However, among week-16 responders, CR rates were significantly higher with UST. Additionally, UST was associated with a significantly greater improvement in QoL compared with anti-TNF.

Journal of Crohn s and ColitisVol. 19(4)
University of Kassel (DE), Goethe University Frankfurt (DE), Goethe-Institute United Kingdom (GB), Kielce University of Technology (PL), Friedrich-Alexander-Universität Erlangen-Nürnberg (DE), Heidelberg University (DE), University Hospital Heidelberg (DE), Christian-Albrechts-Universität zu Kiel (DE), Universitätsklinikum Erlangen (DE), University Hospital Münster (DE), University Hospital Schleswig-Holstein (DE), Hochschule für Technik und Wirtschaft des Saarlandes (DE), Medice (Germany) (DE), University Hospital Leipzig (DE), Vitos Orthopedic Clinic Kassel (DE), Praxis für Humangenetik (DE), IS practice (BE), Institut für Produktqualität (DE), Crohn's and Colitis UK (GB), Comprehensive Cancer Center Erlangen (DE), Klinikum Kassel (DE), Klinikum Saarbrücken (DE), Johannes Wesling Klinikum Minden (DE), Clinical Research Center Kiel (DE), University of Applied Sciences Europe (DE), Heidelberg University (US), University of Lübeck (DE)
Good health and well-being
Openalex Percentile: Top 9%
Inflammatory Bowel Disease
3.63
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