Temporal‐multimodal consistency alignment for Alzheimer's cognitive assessment prediction

In this work, we proposed a novel framework that unifies multimodality fusion with dual-granularity alignment for cognitive assessment forecasting. Our approach utilizes a temporal-multimodal consistency alignment strategy, which effectively synchronizes various modalities within a unified latent space. Furthermore, the innovative HMF block we developed capitalizes on the inherent relationships and dependencies between modalities to optimize data integration. Extensive numerical results on five cognitive assessment scores, supported by detailed visualizations demonstrate the superior performance of our approach compared to existing methods. Our code has been released, and it is available at https://github.com/IcecreamArtist/MM_DURA.

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Publication Details

Journal
Medical Physics
Published
2025-03-25
DOI
https://doi.org/10.1002/mp.17767
Citations
2
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
2.94

Funders

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article

Temporal‐multimodal consistency alignment for Alzheimer's cognitive assessment prediction

Pheng‐Ann Heng, Xi Wang, Xikai Yang, Xilin Dang et al.
2 citations
Medical Physics
Dementia and Cognitive Impairment Research
2.94
article

Temporal‐multimodal consistency alignment for Alzheimer's cognitive assessment prediction

Pheng‐Ann Heng, Xi Wang, Xikai Yang, Xilin Dang, Jinpeng Li, Jinyue Cai
article en
2 citations

Abstract

In this work, we proposed a novel framework that unifies multimodality fusion with dual-granularity alignment for cognitive assessment forecasting. Our approach utilizes a temporal-multimodal consistency alignment strategy, which effectively synchronizes various modalities within a unified latent space. Furthermore, the innovative HMF block we developed capitalizes on the inherent relationships and dependencies between modalities to optimize data integration. Extensive numerical results on five cognitive assessment scores, supported by detailed visualizations demonstrate the superior performance of our approach compared to existing methods. Our code has been released, and it is available at https://github.com/IcecreamArtist/MM_DURA.

Medical PhysicsVol. 52(6)
Chinese University of Hong Kong (HK), Hong Kong University of Science and Technology (HK)
National Natural Science Foundation of China
Openalex Percentile: Top 11%
Dementia and Cognitive Impairment Research
2.94
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