Prostaglandin E1 restores endothelial progenitor cell function in systemic sclerosis
PGE1 treatment restores CFU-EC and ECFC levels in SSc patients, suggesting a potential role in repairing vascular damage. These findings highlight PGE1's therapeutic benefits beyond vasodilation, supporting its use in SSc-associated microvasculopathy.
Authors
- Jan Damoiseaux (ORCID: https://orcid.org/0000-0003-4007-6985)
- Pieter van Paassen (ORCID: https://orcid.org/0000-0001-9366-7995)
- Rachid Tobal (ORCID: https://orcid.org/0009-0005-8255-4801)
- Lucienne Debrus-Palmans
- Suzanne Arends (ORCID: https://orcid.org/0000-0002-4422-7640)
- Judith Potjewijd (ORCID: https://orcid.org/0000-0001-9730-9298)
Institutions
- Maastricht University Medical Centre (NL)
- University Medical Center (US)
- Maastricht University (NL)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1093/rheumatology/keaf174
- Citations
- 2
- Primary Topic
- Systemic Sclerosis and Related Diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.94