Vitamin D and canagliflozin combination alleviates Parkinson’s disease in rats through modulation of RAC1/NF-κB/Nrf2 interaction

These findings suggest that Vit D and CAN synergistically modulate the RAC1/NF-κB/Nrf2 pathway, leading to improved neuroprotection in PD.

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Publication Details

Journal
Immunopharmacology and Immunotoxicology
Published
2025-03-25
DOI
https://doi.org/10.1080/08923973.2025.2481849
Citations
3
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
4.17
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article

Vitamin D and canagliflozin combination alleviates Parkinson’s disease in rats through modulation of RAC1/NF-κB/Nrf2 interaction

Sara G. Tayel, Alzahraa A. M. Sheref, S Rizk, Sara A. El Derbaly et al.
3 citations
Immunopharmacology and Immunotoxicology
Parkinson's Disease Mechanisms and Treatments
4.17
article

Vitamin D and canagliflozin combination alleviates Parkinson’s disease in rats through modulation of RAC1/NF-κB/Nrf2 interaction

Sara G. Tayel, Alzahraa A. M. Sheref, S Rizk, Sara A. El Derbaly, Eman Ali
article en
3 citations

Abstract

These findings suggest that Vit D and CAN synergistically modulate the RAC1/NF-κB/Nrf2 pathway, leading to improved neuroprotection in PD.

Immunopharmacology and ImmunotoxicologyVol. 47(3)
Universitas 17 Agustus 1945 Semarang (ID), Ibn Sina Hospital (KW), Menoufia University (EG)
Good health and well-being
Openalex Percentile: Top 7%
Parkinson's Disease Mechanisms and Treatments
4.17
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