Comparative analysis of auger electron emission libraries and Monte Carlo track structure codes for DNA‐targeted auger electron therapy
The EADL library produces more electrons than McGuire, but this does not affect the amount of local DNA damage significantly, as most of the additional electrons fall below the 17.5 eV damage threshold. Both libraries yield similar DNA damage outcomes. In addition, our analysis highlights the need for specific energy thresholds in MC codes to ensure accurate DNA damage predictions in Auger electron studies.
Authors
- Alexandre França Velo (ORCID: https://orcid.org/0000-0001-9786-4136)
- John L. Humm (ORCID: https://orcid.org/0000-0003-4245-5591)
- Michael Bellamy (ORCID: https://orcid.org/0000-0003-0892-7559)
- Lukas M. Carter (ORCID: https://orcid.org/0000-0003-4848-4190)
- Brian M. Zeglis (ORCID: https://orcid.org/0000-0002-9091-744X)
Institutions
- Memorial Sloan Kettering Cancer Center (US)
- Hunter College (US)
Publication Details
- Journal
- Medical Physics
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1002/mp.17766
- Citations
- 2
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- National Institutes of Health