5-Hydroxymethylcytosine signatures in circulating cell-free DNA as potential diagnostic markers for breast cancer
Our study offers a comprehensive understanding of genome-wide 5hmC in cfDNA from breast cancer patients, and identifies valuable epigenetic biomarkers for the minimally invasive diagnosis of breast cancer.
Authors
- Qiujie Meng (ORCID: https://orcid.org/0000-0002-8753-6718)
- Yangjun Cai
- Yongxia Chen (ORCID: https://orcid.org/0000-0001-7061-695X)
- Lidan Jin (ORCID: https://orcid.org/0000-0002-8985-3362)
- Zhongqiu Zheng
- Jiaheng Lang
- Siwei Ju (ORCID: https://orcid.org/0000-0002-3364-6989)
- Qina He (ORCID: https://orcid.org/0000-0002-5395-4639)
- Nadire Aishan
- Jiahang Zhang (ORCID: https://orcid.org/0009-0002-5360-234X)
- Jun Shen (ORCID: https://orcid.org/0000-0002-8384-3526)
- Linbo Wang (ORCID: https://orcid.org/0000-0003-0526-1990)
- Yi Lu (ORCID: https://orcid.org/0000-0002-1599-8593)
- Feilin Cao (ORCID: https://orcid.org/0000-0003-2662-9440)
- Bojian Xie
- Feiyang Ji (ORCID: https://orcid.org/0000-0002-0710-0739)
Institutions
- Wenzhou Medical University (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
- Hangzhou Medical College (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Biomarkers in Medicine
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1080/17520363.2025.2483156
- Citations
- 1
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- National Natural Science Foundation of China