Ex-vivo Imaging of Glial Energy Metabolism in the Neonatal Mouse Brain during Convulsive Seizures with Intranasal Radiotracer Administration
Quantitative images of biological functions in the neonatal mouse brain can be obtained by intranasal administration. This technique allowed the observation of a decrease in acetate uptake associated with convulsive seizures. The results of this study could be applied to the imaging of biological brain functions and research on neurological disorders using labeled probes in neonatal mice.
Authors
- Takahiro Hayakawa
- Yuya Haga (ORCID: https://orcid.org/0000-0003-4148-2256)
- Rie Hosoi (ORCID: https://orcid.org/0000-0002-4646-9272)
- Kazuya Tada (ORCID: https://orcid.org/0000-0001-5697-4048)
Institutions
- The University of Osaka (JP)
Publication Details
- Journal
- Molecular Imaging and Biology
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1007/s11307-025-02000-9
- Citations
- 1
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.91
Funders
- Osaka University