Distinct Cytokine Responses in Central and Systemic Compartments after Subarachnoid Haemorrhage
SAH provokes an inflammatory response in CSF and plasma. The response pattern is different and distinct in each compartment. Each compartment's relationship with outcomes differ, suggesting separate roles in SAH pathophysiology. Plasma IL-6 is independently associated with outcomes.
Authors
- Chieh‐Hsi Wu (ORCID: https://orcid.org/0000-0001-9386-725X)
- Ben Gaastra (ORCID: https://orcid.org/0000-0002-7517-6882)
- Ian Galea (ORCID: https://orcid.org/0000-0002-1268-5102)
- Patrick Garland (ORCID: https://orcid.org/0000-0002-7679-6426)
- Diederik Bulters (ORCID: https://orcid.org/0000-0001-9884-9050)
- Ardalan Zolnourian (ORCID: https://orcid.org/0000-0002-0428-179X)
- Soham Bandyopadhyay (ORCID: https://orcid.org/0000-0001-6553-3842)
Institutions
- University Hospital Southampton NHS Foundation Trust (GB)
- University of Southampton (GB)
Publication Details
- Journal
- Translational Stroke Research
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1007/s12975-025-01348-y
- Citations
- 1
- Primary Topic
- Intracranial Aneurysms: Treatment and Complications
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Institute for Health and Care Research
- Medical Research Council