Population pharmacokinetic model of oral minocycline in critically ill adult patients with ventilator-associated pneumonia

This study provides a popPK model for oral MIN in critically ill adults. The developed popPK model contributes to a better understanding of MIN's PK and can inform dosing strategies and future studies on MIN use in critical care settings.

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Publication Details

Journal
Journal of Antimicrobial Chemotherapy
Published
2025-03-26
DOI
https://doi.org/10.1093/jac/dkaf090
Citations
2
Primary Topic
Antibiotics Pharmacokinetics and Efficacy
Type
article
Field-Weighted Citation Impact
2.79
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Population pharmacokinetic model of oral minocycline in critically ill adult patients with ventilator-associated pneumonia

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Population pharmacokinetic model of oral minocycline in critically ill adult patients with ventilator-associated pneumonia

Sofia Manioudaki, Aristides Dokoumetzidis, Elmina-Marina Saitani, Vassiliki Koumaki, Athanasios Tsakris, Zoe Athanassa, Paraskevi Papakyriakopoulou, Georgia Valsami, Aikaterini Sakagianni, Irina Petsa, Silvia Marquez Megias, Katerina Dimoula
article en
2 citations

Abstract

This study provides a popPK model for oral MIN in critically ill adults. The developed popPK model contributes to a better understanding of MIN's PK and can inform dosing strategies and future studies on MIN use in critical care settings.

Journal of Antimicrobial ChemotherapyVol. 80(5)
Universitat de Miguel Hernández d'Elx (ES), National and Kapodistrian University of Athens (GR), Sismanoglio General Hospital (GR)
Good health and well-being
Openalex Percentile: Top 12%
Antibiotics Pharmacokinetics and Efficacy
2.79
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