Electrochemical debrominative hydrogenation/deuteration of 2-bromo-<i>N</i>-arylacetamides
Herein, we report a facile and efficient electro-reductive debrominative hydrogenation/deuteration of 2-bromo-<i>N</i>-aryl acetamides using H<sub>2</sub>O/D<sub>2</sub>O as an economical source of hydrogen/deuterium at room temperature. The reactions proceeded efficiently <i>via</i> C-Br bond activation, enabling facile synthesis of a range of <i>N</i>-substituted amides in moderate to high yields with broad functional group compatibility.
Authors
- Maya Shankar Singh (ORCID: https://orcid.org/0000-0002-3199-0823)
- Malkeet Singh (ORCID: https://orcid.org/0009-0002-1977-2310)
- Saurabh Singh (ORCID: https://orcid.org/0000-0002-3715-4439)
- Ashvani K. Singh
Institutions
- Banaras Hindu University (IN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc00530b
- Citations
- 3
- Primary Topic
- Chemical Reactions and Isotopes
- Type
- article
- Field-Weighted Citation Impact
- 2.37