Hyperketonemic cows with high liver health index and low NEFA levels at diagnosis respond better to propylene glycol treatment

Prior research has yielded conflicting findings regarding the efficacy of treatments for hyperketonemia (HYK), with the re­sponse varying depending on the metabolic status of the cow. Early lactation concentrations of non-esterified fatty acids (NEFA) and liver health index (LHI) – an index associated with the inflammatory response calculated based on plasma biliru­bin, albumin, and cholesterol – are used to determine if the cow successfully transitioned to lactation. Our study aimed to assess the effect of propylene glycol on the persistence of HYK in cows with different concentrations of NEFA and LHI at HYK diagnosis.

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Publication Details

Journal
American Association of Bovine Practitioners Conference Proceedings
Published
2025-03-26
DOI
https://doi.org/10.21423/aabppro20249177
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Hyperketonemic cows with high liver health index and low NEFA levels at diagnosis respond better to propylene glycol treatment

L.S. Caixeta, Shanlee Davis, Megan Ruch, Elise Shepley et al.
American Association of Bovine Practitioners Conference Proceedings
Liver Disease Diagnosis and Treatment
article

Hyperketonemic cows with high liver health index and low NEFA levels at diagnosis respond better to propylene glycol treatment

L.S. Caixeta, Shanlee Davis, Megan Ruch, Elise Shepley, M. Dorella, C. Florentino
article en

Abstract

Prior research has yielded conflicting findings regarding the efficacy of treatments for hyperketonemia (HYK), with the re­sponse varying depending on the metabolic status of the cow. Early lactation concentrations of non-esterified fatty acids (NEFA) and liver health index (LHI) – an index associated with the inflammatory response calculated based on plasma biliru­bin, albumin, and cholesterol – are used to determine if the cow successfully transitioned to lactation. Our study aimed to assess the effect of propylene glycol on the persistence of HYK in cows with different concentrations of NEFA and LHI at HYK diagnosis.

American Association of Bovine Practitioners Conference ProceedingsVol. 58(58)
University of Minnesota (US)
Openalex Percentile: Top 91%
Liver Disease Diagnosis and Treatment
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Hyperketonemic cows with high liver health index and low NEFA levels at diagnosis respond better to propylene glycol treatment — L.S. Caixeta, Shanlee Davis, et al. · American Association of Bovine Practitioners Conference Proceedings (2025) | TGRS Research Map | TGRS