Network analysis of splenic gene expression of cattle co-infected with bovine viral diarrhea virus 2 and bovine herpes virus 1 following vaccination and trace mineral administration
A common management practice to prevent bovine respiratory disease (BRD) in dairy and beef cattle often involves the administration of modified-live virus (MLV) vaccines. In addition, injectable trace minerals (ITM) concomitant with vaccination has been associated with an improved immune response and protection elicited by vaccine antigens. While widely utilized, the influence these tools have on immunomodulation and cellular mobilization within central lymphoid tissue is largely unknown. To our knowledge, this study is the first to comprehensively evaluate gene expression patterns from cattle administered MLV vaccines and ITM followed by BVDV2 and BHV1 challenge.
Authors
- Erika A. González Altamiranda (ORCID: https://orcid.org/0000-0001-7193-0262)
- A. Rodríguez (ORCID: https://orcid.org/0000-0003-3617-0119)
- Alejandro Hoyos‐Jaramillo (ORCID: https://orcid.org/0000-0001-7125-1120)
- Roberto A. Palomares (ORCID: https://orcid.org/0000-0002-3390-5098)
- J.H.J. Bittar (ORCID: https://orcid.org/0000-0002-6440-6785)
- Michelle Scott (ORCID: https://orcid.org/0000-0002-6755-9373)
- José Ramón Urdaneta Machado (ORCID: https://orcid.org/0000-0002-6972-1522)
- M.K. Linson
Institutions
- University of Georgia (US)
- West Texas A&M University (US)
- University of Florida (US)
- National Agricultural Technology Institute (AR)
Publication Details
- Journal
- American Association of Bovine Practitioners Conference Proceedings
- Published
- 2025-03-26
- DOI
- https://doi.org/10.21423/aabppro20249165
- Primary Topic
- Animal Disease Management and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00