Lipid profiles, lipid ratios and 28-day mortality risk in non-surgical older patients with critical illnesses: a retrospective cohort study using hospitalization records
Lower levels of LDLC and its subtypes (lbLDLC, sdLDLC) were associated with increased 28-day mortality risk, particularly in patients aged ≥ 75 years and women. Conversely, elevated residual cholesterol levels correlated with higher mortality in younger older adults (< 75 years). These findings underscore the need for age- and sex-specific lipid management strategies in older patients with critical illnesses.
Authors
- Shasha Geng (ORCID: https://orcid.org/0000-0002-7443-1618)
- Yingqian Zhu (ORCID: https://orcid.org/0000-0001-7452-1536)
- Yang Li (ORCID: https://orcid.org/0000-0002-9717-7755)
- Qingqing Li (ORCID: https://orcid.org/0000-0002-1154-3719)
- Xin Chen (ORCID: https://orcid.org/0000-0002-1920-8835)
- Xiaotong Guo
- Yue Liu (ORCID: https://orcid.org/0000-0003-1759-9147)
- Hongjie Gu
- Jianli Ge (ORCID: https://orcid.org/0000-0002-4099-5474)
Institutions
- Shanghai East Hospital (CN)
- Yangpu Hospital of Tongji University (CN)
Publication Details
- Journal
- Lipids in Health and Disease
- Published
- 2025-03-27
- DOI
- https://doi.org/10.1186/s12944-025-02545-2
- Citations
- 1
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 1.16