Candidal speciation and carriage in oral cavity of HIV-positive children/adults and healthy individuals in the South Canara district of India: a comparative study
The proportion and quantity of candidal colonization was higher in HIV-positive children (93.30%) as compared to adults (67.50%). An increased profile of Nakaseomyces glabrata (previously Candida glabrata) was seen in children while the adults showed increase in colonization of C. tropicalis. The shift in profiles of species from Candida albicans to 'non-albicans' Candida species is of clinical relevance as it directly impacts on the antimicrobial efficacy of chosen anti-fungal agents.
Authors
- John Ramapuram (ORCID: https://orcid.org/0000-0002-9441-5746)
- Nunna Sai Chitra
- Nidhi Manaktala (ORCID: https://orcid.org/0000-0001-9084-3383)
- Matthew D. Solomon (ORCID: https://orcid.org/0000-0001-7846-9296)
- Srikant Natarajan (ORCID: https://orcid.org/0000-0002-2686-0397)
- Shrikala Baliga (ORCID: https://orcid.org/0000-0002-6722-1532)
- Karen Boaz (ORCID: https://orcid.org/0000-0001-6033-9581)
- Sneha KS
Institutions
- Manipal Academy of Higher Education (IN)
- Kasturba Medical College, Manipal (IN)
Publication Details
- Journal
- BMC Research Notes
- Published
- 2025-03-27
- DOI
- https://doi.org/10.1186/s13104-025-07190-7
- Citations
- 1
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 1.40