Connexin46 in the nucleus of cancer cells: a possible role as transcription modulator

Our findings reveal a novel nuclear role for Cx46 in cancer, demonstrating its function as a transcriptional regulator and its potential as a therapeutic target.

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Publication Details

Journal
Cell Communication and Signaling
Published
2025-03-27
DOI
https://doi.org/10.1186/s12964-025-02151-w
Citations
3
Primary Topic
Connexins and lens biology
Type
article
Field-Weighted Citation Impact
2.42
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article

Connexin46 in the nucleus of cancer cells: a possible role as transcription modulator

Mauricio A. Retamal, Fabio Mammano, Viviana P. Orellana, Iván E. Alfaro et al.
3 citations
Cell Communication and Signaling
Connexins and lens biology
2.42
article

Connexin46 in the nucleus of cancer cells: a possible role as transcription modulator

Mauricio A. Retamal, Fabio Mammano, Viviana P. Orellana, Iván E. Alfaro, Alberto J. M. Martín, Juan F. Calderón, Ainoa Fernández-Olivares, Sebastián Contreras-Riquelme, Mauricio Sáez, Jesús Llanquinao, Jimmy Stehberg, Gonzalo Núñez, Pablo Ernesto Pérez
article en
3 citations

Abstract

Our findings reveal a novel nuclear role for Cx46 in cancer, demonstrating its function as a transcriptional regulator and its potential as a therapeutic target.

Cell Communication and SignalingVol. 23(1)
Universidad del Desarrollo (CL), Universidad Andrés Bello (CL), Clínica Alemana (CL), Universidad Católica de Temuco (CL), San Sebastián University (CL), Fundación Ciencia and Vida (CL), Fundación Arturo López Pérez (CL), National Research Council (IT)
Zero hunger
Openalex Percentile: Top 12%
Connexins and lens biology
2.42
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