Long-term immune responses to SARS-CoV-2 Omicron BA.4/5 mRNA booster in people living with HIV
The original-BA.4/5 bivalent booster is highly immunogenic in PLWH and superior to the monovalent one in inducing humoral responses against the BA.4/5 virus, although HIV-related T cell dysfunction markers are associated with blunted and less durable antibody immunity.
Authors
- Andrea Santoro (ORCID: https://orcid.org/0000-0001-7959-2958)
- Alessandro Tavelli (ORCID: https://orcid.org/0000-0001-5899-451X)
- Stefania Notari (ORCID: https://orcid.org/0000-0002-7692-6606)
- Roberta Rovito (ORCID: https://orcid.org/0000-0002-8640-844X)
- Andrea Antinori (ORCID: https://orcid.org/0000-0003-2121-4684)
- Camilla Tincati (ORCID: https://orcid.org/0000-0002-3083-2962)
- Fabrizio Maggi (ORCID: https://orcid.org/0000-0001-7489-5271)
- Silvia Meschi (ORCID: https://orcid.org/0000-0003-0924-993X)
- Gianluca Spiteri (ORCID: https://orcid.org/0000-0001-8536-7095)
- Anna Maria Azzini (ORCID: https://orcid.org/0000-0002-7148-2559)
- Elda Righi (ORCID: https://orcid.org/0000-0001-8718-1200)
- Alessandra Vergori (ORCID: https://orcid.org/0000-0001-6944-0686)
- Stefano Porru (ORCID: https://orcid.org/0000-0003-3564-7202)
- Matteo Augello (ORCID: https://orcid.org/0000-0002-1031-9504)
- Giulia Marchetti (ORCID: https://orcid.org/0000-0002-4498-4828)
- Valeria Bono (ORCID: https://orcid.org/0000-0003-2182-5434)
- Evelina Tacconelli
- Antonella d’Arminio Monforte
Institutions
- University of Verona (IT)
- AOL (United States) (US)
- University of Milan (IT)
- Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani (IT)
- Ospedale San Paolo (IT)
Publication Details
- Journal
- Communications Medicine
- Published
- 2025-03-27
- DOI
- https://doi.org/10.1038/s43856-025-00799-6
- Citations
- 2
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 2.79
Funders
- Horizon 2020 Framework Programme