Unraveling anoikis in glioblastoma: insights from single-cell sequencing and prognostic modeling
This study provides insights into the molecular mechanisms of anoikis resistance in GBM, underscoring its critical role in tumor progression and patient prognosis. The developed prognostic model offers a promising tool for personalized treatment strategies and warrants further exploration of targeted therapies to improve outcomes for GBM patients.
Authors
- Zongren Wan
- Chenfeng Ma
- Qikai Tang (ORCID: https://orcid.org/0000-0003-0712-6338)
- Weiqi Bian
- Qingyu Lu
- Jiaheng Xie (ORCID: https://orcid.org/0000-0002-4992-498X)
- Qixiang Zhang (ORCID: https://orcid.org/0000-0001-5690-0065)
- Bingtao Zhang (ORCID: https://orcid.org/0000-0002-6865-0304)
- Wei Wu (ORCID: https://orcid.org/0000-0003-4228-2416)
Institutions
- Central South University (CN)
- Xuzhou Medical College (CN)
- Shanghai Jiao Tong University (CN)
- Nanjing General Hospital of Nanjing Military Command (CN)
- Ruijin Hospital (CN)
- Jiangsu Province Hospital (CN)
- Xiangya Hospital Central South University (CN)
- Nanjing Medical University (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1186/s12935-025-03752-8
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00