Mid Term Evaluation of Patients Undergoing Surgery for Tetralogy of Fallot with 24 Hour Rhythm Holter and Cardiopulmonary Exercise Testing

Objective: This study aimed to obtain mid-term evaluation of exercise capacity and arrhythmias with cardiopulmonary exercise testing (CPET) and 24-hour rhythm Holter in Tetralogy of Fallot (TOF) patients who underwent surgery. Materials and Methods: The study group consisted of patients over 6 years of age who had undergone complete correction surgery for TOF, while the control group consisted of healthy children of a similar age group who did not have any heart disease. Echocardiography, 24-hour Holter monitoring and CPET were applied to both groups. Results: Study group included 14 patients who were operated on due to TOF and 9 healthy children as the control group. During echocardiographic examination; aortic diameter, pulmonary annulus, right ventricular (RV) systolic and diastolic areas were found to be significantly larger in the patient group (p=0.044, p=0.017, p=0.05, p=0.012 respectively). Myocardial performance index (Tei index-MPI) calculated from mitral and tricuspid valve annulus was found to be significantly higher in the patient group (p=0.05 for both). During CPET, stroke volume and VO2max levels were significantly smaller in patients (p=0.004, p=0.044 respectively). Conclusion: Although operated TOF patients are asymptomatic in the mid-term, the exercise capacity in these patients is lower than in healthy individuals and this decrease is related to right ventricular size and dysfunction.

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Publication Details

Journal
Sakarya Medical Journal
Published
2025-03-26
DOI
https://doi.org/10.31832/smj.1545544
Primary Topic
Congenital Heart Disease Studies
Type
article
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article

Mid Term Evaluation of Patients Undergoing Surgery for Tetralogy of Fallot with 24 Hour Rhythm Holter and Cardiopulmonary Exercise Testing

Figen Akalın, Nazife Reyyan Gök, Elif Erolu
Sakarya Medical Journal
Congenital Heart Disease Studies
article

Mid Term Evaluation of Patients Undergoing Surgery for Tetralogy of Fallot with 24 Hour Rhythm Holter and Cardiopulmonary Exercise Testing

Figen Akalın, Nazife Reyyan Gök, Elif Erolu
article en

Abstract

Objective: This study aimed to obtain mid-term evaluation of exercise capacity and arrhythmias with cardiopulmonary exercise testing (CPET) and 24-hour rhythm Holter in Tetralogy of Fallot (TOF) patients who underwent surgery. Materials and Methods: The study group consisted of patients over 6 years of age who had undergone complete correction surgery for TOF, while the control group consisted of healthy children of a similar age group who did not have any heart disease. Echocardiography, 24-hour Holter monitoring and CPET were applied to both groups. Results: Study group included 14 patients who were operated on due to TOF and 9 healthy children as the control group. During echocardiographic examination; aortic diameter, pulmonary annulus, right ventricular (RV) systolic and diastolic areas were found to be significantly larger in the patient group (p=0.044, p=0.017, p=0.05, p=0.012 respectively). Myocardial performance index (Tei index-MPI) calculated from mitral and tricuspid valve annulus was found to be significantly higher in the patient group (p=0.05 for both). During CPET, stroke volume and VO2max levels were significantly smaller in patients (p=0.004, p=0.044 respectively). Conclusion: Although operated TOF patients are asymptomatic in the mid-term, the exercise capacity in these patients is lower than in healthy individuals and this decrease is related to right ventricular size and dysfunction.

Sakarya Medical JournalVol. 15(1)
Marmara University (TR)
Openalex Percentile: Top 91%
Congenital Heart Disease Studies
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