Periorbital edema and phototoxic rash associated with dasatinib: A case report

Dasatinib is an effective agent in the treatment of bcr-abl positive acute lymphoblastic leukemia and chronic myeloid leukemia cases. Various skin reactions may occur when tyrosine kinase inhibitors are used. The severity of side effects increases in phototoxic reactions with sunlight. In this case, a phototoxic rash that developed in a 78-year-old bcr-abl positive acute lymphoblastic leukemia patient is presented. This case supports that phototoxic reactions may occur with dasatinib and emphasizes that clinicians should be alert for this side effect.

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Publication Details

Journal
SAGE Open Medical Case Reports
Published
2025-03-25
DOI
https://doi.org/10.1177/2050313x251330969
Citations
2
Primary Topic
Chronic Myeloid Leukemia Treatments
Type
article
Field-Weighted Citation Impact
3.54
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article

Periorbital edema and phototoxic rash associated with dasatinib: A case report

Ümi̇t Yavuz Malkan, Burcu Uğurlu
2 citations
SAGE Open Medical Case Reports
Chronic Myeloid Leukemia Treatments
3.54
article

Periorbital edema and phototoxic rash associated with dasatinib: A case report

Ümi̇t Yavuz Malkan, Burcu Uğurlu
article en
2 citations

Abstract

Dasatinib is an effective agent in the treatment of bcr-abl positive acute lymphoblastic leukemia and chronic myeloid leukemia cases. Various skin reactions may occur when tyrosine kinase inhibitors are used. The severity of side effects increases in phototoxic reactions with sunlight. In this case, a phototoxic rash that developed in a 78-year-old bcr-abl positive acute lymphoblastic leukemia patient is presented. This case supports that phototoxic reactions may occur with dasatinib and emphasizes that clinicians should be alert for this side effect.

SAGE Open Medical Case ReportsVol. 13
Hacettepe University (TR)
Good health and well-being
Openalex Percentile: Top 9%
Chronic Myeloid Leukemia Treatments
3.54
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