Astragalus mongholicusbunge and Angelica sinensis botanical drug decoction mitigates lung inflammation through NOX4/TGF-β1/SMAD3 signaling
These findings demonstrate the lung-protecting function of DBT in a rat model and identify critical target proteins associated with the underlying mechanism.
Authors
- Wenwen Sui
- Ping Dai
- Tong Zhou (ORCID: https://orcid.org/0000-0002-3158-1616)
- Wei Yuan (ORCID: https://orcid.org/0000-0002-2728-6841)
- Chengli Wen (ORCID: https://orcid.org/0000-0001-8956-8898)
- Yuqian Chang (ORCID: https://orcid.org/0000-0002-8930-6860)
- Jun Zhou (ORCID: https://orcid.org/0000-0003-1173-0845)
- Jia-Sheng Wang (ORCID: https://orcid.org/0000-0002-8458-9187)
- Zhifeng Yang
- Haidong Zhang (ORCID: https://orcid.org/0009-0009-8850-6893)
Institutions
- University of Georgia (US)
- Wenzhou Medical University (CN)
- Dongyang People's Hospital (CN)
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
- Shandong First Medical University (CN)
- Shandong Center for Disease Control and Prevention (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-03-26
- DOI
- https://doi.org/10.3389/fphar.2025.1565569
- Citations
- 4
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 6.07