Development of ROBUST-RCT: Risk Of Bias instrument for Use in SysTematic reviews-for Randomised Controlled Trials
Recent innovations in evidence based medicine methods, in particular instruments assessing risk of bias in randomised trials, have focused on methodological rigour at the expense of simplicity and practicability. Such a focus could lead to challenges in application and loss of reliability of instruments. To deal with these shortcomings, the Risk Of Bias instrument for Use in SysTematic reviews-for Randomised Controlled Trials (ROBUST-RCT) was created—a rigorously developed, simply structured, and user friendly instrument for assessing risk of bias of randomised controlled trials included in systematic reviews. This paper describes the development of ROBUST-RCT and provides associated documents and a manual of instructions.
Authors
- Carrol L. Gamble (ORCID: https://orcid.org/0000-0002-3021-1955)
- Luz María Letelier S (ORCID: https://orcid.org/0000-0002-4150-2985)
- Paul Glasziou (ORCID: https://orcid.org/0000-0001-7564-073X)
- Matthias Briel (ORCID: https://orcid.org/0000-0002-2070-5230)
- Gordon Guyatt (ORCID: https://orcid.org/0000-0003-2352-5718)
- Dena Zeraatkar (ORCID: https://orcid.org/0000-0003-4287-0541)
- Elie A. Akl (ORCID: https://orcid.org/0000-0002-3444-8618)
- Sheri A. Keitz (ORCID: https://orcid.org/0000-0001-5828-0883)
- Philippe Ravaud (ORCID: https://orcid.org/0000-0001-8264-9206)
- Kenneth F. Schulz (ORCID: https://orcid.org/0000-0003-2596-7616)
- Dirk Bassler (ORCID: https://orcid.org/0000-0003-2358-4419)
- Reed Siemieniuk (ORCID: https://orcid.org/0000-0002-3725-3031)
- Jane L. Hutton (ORCID: https://orcid.org/0000-0003-0963-9997)
- Susan Armijo‐Olivo (ORCID: https://orcid.org/0000-0001-7942-433X)
- Ying Wang (ORCID: https://orcid.org/0000-0002-2296-1991)
- David Torgerson (ORCID: https://orcid.org/0000-0002-1667-4275)
- Romina Brignardello-Petersen
- Lise Lotte Gluud (ORCID: https://orcid.org/0000-0002-9462-4468)
Institutions
- University of North Carolina at Chapel Hill (US)
- Bond University (AU)
- University of Liverpool (GB)
- University of Alberta (CA)
- Inserm (FR)
- Pontificia Universidad Católica de Chile (CL)
- Beijing University of Chinese Medicine (CN)
- University of Basel (CH)
- University of Zurich (CH)
- Université Paris Cité (FR)
- University Hospital of Basel (CH)
- Copenhagen University Hospital (DK)
- University of Warwick (GB)
- Sorbonne Paris Cité (FR)
- University Hospital of Zurich (CH)
- Hochschule Osnabrück (DE)
- Impact (CA)
- Centre de Recherche Épidémiologie et Statistique (FR)
- University of York (GB)
- McMaster University (CA)
- American University of Beirut (LB)
Publication Details
- Journal
- BMJ
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1136/bmj-2024-081199
- Citations
- 21
- Primary Topic
- Meta-analysis and systematic reviews
- Type
- article
- Field-Weighted Citation Impact
- 30.77