Pan-cancer clinical and molecular landscape of MTAP deletion in nationwide and international comprehensive genomic data
MTAP deletion is associated with unique clinical and molecular features. These findings define the characteristics of MTAP-deleted cancers and provide a basis for synthetic lethal strategies in precision oncology.
Authors
- Katsutoshi Oda (ORCID: https://orcid.org/0000-0002-2468-9573)
- Hidenori Kage (ORCID: https://orcid.org/0000-0003-3658-4442)
- Aya Shinozaki‐Ushiku (ORCID: https://orcid.org/0000-0002-0196-5643)
- Kousuke Watanabe (ORCID: https://orcid.org/0000-0003-4670-3679)
- Hiroaki Ikushima (ORCID: https://orcid.org/0000-0002-7053-2841)
Institutions
- The University of Tokyo (JP)
Publication Details
- Journal
- ESMO Open
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1016/j.esmoop.2025.104535
- Citations
- 14
- Primary Topic
- Cancer-related gene regulation
- Type
- article
- Field-Weighted Citation Impact
- 11.28