A novel senotherapeutic strategy with azithromycin for preventing endometriosis progression
Our findings show that cellular senescence is involved in the pathogenesis of endometriosis and that AZM may be useful for preventing endometriosis progression by suppressing the secretion of IL-6 as a SASP.
Authors
- Reina Sonehara (ORCID: https://orcid.org/0009-0004-2807-2177)
- Tomoko Nakamura (ORCID: https://orcid.org/0000-0001-5987-4384)
- Takehiko Takeda
- Satoko Osuka (ORCID: https://orcid.org/0000-0002-4430-7982)
- Atsushi Yabuki
- Natsuki Miyake (ORCID: https://orcid.org/0000-0003-4539-4798)
- Ayako Muraoka (ORCID: https://orcid.org/0000-0003-2203-0844)
- Akira Iwase (ORCID: https://orcid.org/0000-0002-0031-884X)
- S Kaseki
- Hideaki Tanaka (ORCID: https://orcid.org/0009-0000-0142-0574)
- Hiroaki Kajiyama
- Tomomi Seki (ORCID: https://orcid.org/0009-0008-9317-8233)
Institutions
- Gunma University (JP)
- Nagoya University Hospital (JP)
- Nagoya University (JP)
Publication Details
- Journal
- Reproductive Biology and Endocrinology
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1186/s12958-025-01381-4
- Citations
- 5
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 8.49
Funders
- Japan Society for the Promotion of Science