Proactive pharmacogenomics in azathioprine-treated pediatric inflammatory bowel disease at a Chinese tertiary hospital
<i>NUDT15</i> C415T is prevalent in China and is associated with an increased risk of azathioprine-induced myelosuppression. A reduced dose of azathioprine should be considered for Chinese pediatric patients with IBD, even in those with normal pharmacogenetic profiles.
Authors
- Cassandra Long (ORCID: https://orcid.org/0000-0002-8000-2481)
- Ying Huang (ORCID: https://orcid.org/0000-0003-4246-1895)
Institutions
- Children's Hospital of Fudan University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-03-26
- DOI
- https://doi.org/10.3389/fphar.2025.1558897
- Citations
- 1
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 1.88
Funders
- National Natural Science Foundation of China