Genipin attenuates oxidative damage in periodontal tissues by alleviating mitochondrial dysfunction and abnormal glucose uptake through inhibition of UCP2
GP regulates oxidative damage in periodontal tissues by maintaining mitochondrial homeostasis, promoting glucose transporter expression, and enhancing glucose uptake, with UCP2 playing a central role.
Authors
- Xinchan Liu
- Weixian Yu (ORCID: https://orcid.org/0000-0002-2401-2845)
- Xirui Xin (ORCID: https://orcid.org/0000-0001-7825-384X)
- Yaqi Shang
- Mengting Hu
- Yu Deng
- Ruobing Fu
- Yubo Hou (ORCID: https://orcid.org/0000-0001-9575-6940)
Institutions
- Jilin University (CN)
- Wenzhou Medical University (CN)
- Stomatology Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-03-26
- DOI
- https://doi.org/10.3389/fphar.2025.1446574
- Citations
- 2
- Primary Topic
- Advanced Glycation End Products research
- Type
- article
- Field-Weighted Citation Impact
- 2.64