Network topology and cannabis use following two weeks of monitored abstinence: moderation of sex and patterns of use findings

The present findings suggest that subtle differences in resting-state network topology associated with CU may persist after an extended period of abstinence in young adults, particularly males, especially those with heavier past-year use and those who initiated CU earlier in life. While further replication is required in larger samples, these findings suggest potential neuroimaging correlates underlying long-term changes in brain network topology associated with CU.